Dothiepin Vs. Fluoxetine (Mechanism Of Action And Pharmacodynamics) Es

Dothiepin Vs. Fluoxetine (Mechanism Of Action And Pharmacodynamics) Comparison Between Mechanism of Action and Pharmacodynamics of Dothiepin and Fluoxetine Description of medicines Mechanism of action and pharmacodynamics Dothiepin Dothiepin is a tricyclic antidepressant. It acts by promoting the effectiveness of several amines (dopamine, norepinephrine, and 5-hydroxytryptamine, which is also known as 5HT and serotonin). It functions by inhibiting their reuptake at the terminals of nerve cells, thus leading to their prolonged presence at the synaptic cleft and an increased effect on the neuron.(1) The reuptake pumps for the above amines are responsible for reducing the concentration of these amines. Dothiepin works by blocking the pumps. According to the amine hypothesis, a decreased concentration of the amines and the resulting decrease in amine dependant synaptic transmission is associated with depression, therefore an increase in the above would help relieve the symptoms of depression. (2) Dothiepin has other actions as well. It reduces norepinephrine induced CAMP formation in the brain, as well as inhibiting the uptake of 5HT into platelets. It also has some anticholinergic and antihistaminic activity.(3) Dothiepin begins to take effect after approximately 2-3 weeks. Usual daily doses of Dothiepin range from 75mg to 200mg in the more severe cases. (2) Fluoxetine Fluoxetine belongs to a group of antidepressants known as the SSRI's, or Selective serotonin reuptake inhibitors. It functions is similar to that of dothiepin above. It also acts as a reuptake inhibitor, but is highly selective. It only inhibits 5HT reuptake, and lacks many of the less useful functions of dothiepin, such as the antihistaminic properties. (1) As above the result in increase in the presence of serotonin at the synaptic cleft results in a decrease in many symptoms of depression. Fluoxetine does however have some side effects including nausea, tremors, loss of libido and in some cases decreased sexual function. (2) It is also possible that it may have an effect on dopamine function. In some cases it also reduces sleep efficiency. (3) Daily doses of Fluoxetine range between 10mg and 60mg. However it has been found that effectiveness does not appear to be strongly related to dose. 20mg is as affective as 40mg, and there is some evidence to suggest that higher doses may be even less effective. However the lower doses result in fewer and less sever adverse effects.(3) Adverse effects or adverse drug interactions Dothiepin Adverse effects of dothiepin range from potentially life threatening to mildly discomforting. Fatalities associated with dothiepin include cardiac failure, neonatal cardio-respiratory failure, myocardial infarction, arrhythmia, cardiac arrest, ventricular fibrillation, stroke, congenital heart disease, haematemesis, aplastic anemia, leukopenia, hepatorenal syndrome, cholestatic jaundice, coma, neuroleptic malignant syndrome, aggravated Parkinson's disease, intrauterine death, renal failure, respiratory arrest. These however are very rare. (1) Other severe side effects include hepatitis, inappropriate ADH secretion, hypomania, and convulsions. Psychotic manifestations, e.g. paranoid delusions, may be brought about or worsened if already present. These symptoms are also very uncommon, though less life threatening than those listed above.(3) The less dangerous side effects are a bit more common, found in many patients, particularly those on higher doses of the drug. These include dry mouth, tachycardia, constipation, drowsiness, sweating, nausea, vomiting, diarrhea, tremor, rashes, and interference with sexual function.(3) The greatest dangers in overdose stem from convulsions, and the cardiac and respiratory effects listed above. (3) Adverse drug interactions include MAO inhibitors and SSRI's as concurrent administration may lead to increased plasma tricyclic levels. CNS depressants, including alcohol will also have an increased effect when taken in conjunctions with dothiepin. Anesthetics may increase the risk of arrhythmia. Antihypertensive agent activity may be reduced by dothiepin. Barbiturates may decrease the serum concentration of dothiepin, while methyl phenidate may increase it. Smoking may reduce the serum concentration of dothiepin by increasing its metabolism. (1) Fluoxetine Fluoxetine appears to have a lower incidence of adverse reactions, and these appear less severe than those associated with dothiepin. (2) Up to 1990 a total of 11 deaths that may be associated with fluoxetine were recorded in patients. However these were not NECESSARILY associated with the drug. The potentially life threatening side effects included hyponatremia, which appeared to be reversible when the patients stopped taking the drug. A very few cases of vasculitis have also been diagnosed. Cases of seizures and seizure like episodes in fluoxetine patients have also been recorded. Some patients developed mania.

Case SDM Essays

Case SDM Essays Case SDM Essay Case SDM Essay What would be your suggestions for distribution channel for mushrooms? B. Possible Solutions Consumer awareness can be created by test marketing. Through sales persons and customer response to the product. Samples can be distributed in big malls and Variety stores. Awareness can also be created through outdoor publicity such as wall hoardings, banners, insertions in news papers etc. Targeted Customers: Hotels * Household sector * Restaurants * Industrial canteens Brand name of the company along with the product can also be highlighted to the customer by using the concept of event marketing. For different kinds of selling modes they can target different customers Institutional sale: Hotel / Restaurants/longitudinal canteens Individual sale: Household Approach to hotel industry can be made and product benefit can be shown to convince the customer. Mushroom related recipe booklet can be given to them for use. Can approach the T. V programs for Khan Khan to show different recipes of Mushrooms in their shows. Dealer push through sales promotion campaign. Press meetings can be a way to consumer awareness. Editors, ruinations of newspapers having maximum circulation can be contacted and samples to be distributed to them (such as 250 GM or 100 GM packs). Packaging should be attractive. Distribution network: Product having being perishable, company should go for faster and effective distribution network having cold storage facility. Distribution through company livery vans In local market Ana Lustrously markets. Network Sales person Chain Store Telemarketing Manufacturer Supplier Retailer Customer Order Case Study 2 Indian Refrigerator Market tongue n rail or road transport t to roan Indians Refrigerator market estimated at RSI. 750 Cry. Is catered mainly by 10 brands. The annual capacity is estimated at around 4. 15 million units is running head of demand of 1. 5 millions. As there is a demand and a surplus supply, all the manufacturers are trying out for new strategies in the market. Times have changed and also the buying behavior of the customer. Earlier it was cash and carry system. Now dealers play an important role in selling; now the systems is exchange for old bring your old refrigerator and take a new one with many gifts. A new company by name Electrocute has entered the market which has acquired Lankly, Cultivator and Volta brand. Researchers have revealed that urban and city sales are declining and hence all manufacturers are trying to concentrate on rural markets. Electrocute strategy is customization of market, with special attention to the Northern and Southern India markets, while Godard the main player thinks that dealer network in rural market for sales and service will be beneficial and is trying to give more emphasis on dealer network, whereas Whirlpool has adopted the strategy of increasing the dealer network by 30%. The market shares of the major players are as follows: God reek Evidence Cultivator Lankly Volta Whirlpool Deadwood Others 5% 27% 1% 1 . Could the refrigerator market be segmented on geographical base planned by Electrocute? 2. What would be the marketing mix for rural market? 3. Wicked 125 L and 150 L models be an ideal choice to launch in rural market? 1 . The main Justification for Electrocute strategy would be Electrocute is amalgamation of 3 companies, Cultivator, Volta and Lankly. Lankly is popular in South Indian racket, while Cultivator is famous in North India Market. Electrocute wants to cash in on the popularity of the respective brands. It is not possible to segment according to North or South Indian Market, once a companys name becomes a logo, then the reason for buying for customers for other brand depends upon price, quality, usability and features of the product. The storage pattern of foods in North India and South India is same. Same is the case of rest of India, so it wont be possible to segregate the market according to the geographical base. 2. The rural market is small but significant as far as refrigerator is concerned. Moreover, the cost of selling of dealer in the rural market should also be Justified. The type of food the rural people consume should also be taken into account; they prefer to have more of natural foods and less of derived food products like Ice- creams, Utter, scenes etc. I nee cost AT ten retaliatory snouts De less attractive to buy. The size and material should be so adjusted that the cost price would be reasonable. The capacity of the refrigerator should be 100 1 300 1. Much more space as to be given for storing vegetables. Other important factor to be taken into consideration is the Power supply which is not so good in rural areas. To avoid the voltage fluctuations in built stabilizers will be the selling features in the rural areas. 3. The chances of selling of 125 1 and 150 1 refrigerators are high because the prices of the refrigerators would be less. This would be a major factor. The second aspect would be they dont have many items to store. They would prefer a small refrigerator, also the space in their homes are not very big wherein a small refrigerator would serve their needs.

The concept of genre in studying Die Hard. (1988) Assignment

The concept of genre in studying Die Hard. (1988) - Assignment Example 67). In order for a successful Action film, the expectations of the readers ought to be fulfilled to enable the listeners to be fascinated and interested. Action is the most appropriate genre that I have chosen with respect to the Die Hard film of 1988. The entire movie is an action genre movie. Genres in respect to film are diverse forms of recognizable classifications of films recurrent with similar acknowledgeable patterns, syntax and filming conventions that include: backgrounds and props, substance and subject matter, themes, period, mood, motifs, structures, plot, circumstances, central narrative events, recurring icons, characterizations and stars. Numerous films are viewed as hybrids because they include multiple film genres. With regards to definitions, genre itself is a French word meaning type or kind. It can, therefore, be said the kind of a movie is principally the type or category a movie falls into for instance Comedy, action, western, thriller, horror and numerous others (Wright, 2004 p. 35). Genres are also sub-classified according to unique qualities for example horror genre, sub-classes are the supernatural, gothic, ghost films, occult, monster movies, slashers, psychological horror, body horror, gore movies, splatter and many others (Dixon, 2000 p. 101). Some film professionals develop new genres and sub-genres to explain amalgamation of films such as action comedies. Universally, nonetheless, many films created in a given type, for instance, film noir follow the fundamental construction and plot shapes of that particular kind. Genres assist the audience in movie choice as well as indicate for whom a given film was created and what they should anticipate seeing for instance in an action film such as the Die hard, the audience expect to see hard work that involve, use of heavy artillery, use of choppers, massive destruction of vehicles,

Toyota Foundation in Toyota Motor Corporation Essay

Toyota Foundation in Toyota Motor Corporation - Essay Example Through the visits to the US and Europe, and the research that he carried out, Kiichiro Toyoda gained a lot of insight and knowledge about automobile production. In 1933, the Toyota Automatic Loom Works Ltd established the Toyoda automobile department. This led to the creation TMC in 1937 as a separate and independent company, with Kiichiro Toyoda as its president (Toyota Motor Corporation 1). Before becoming a separate and independent company in 1937, TMC had already produced and sold its first standard passenger car, the AA sedan, in 1936. TMC got its logo from a public competition held in September 1936, in which participants were required to design the best logo. Toyoda then changed its name to Toyota, trademarked its new name, and registered itself as the TMC in August 1937. TMC officially began its commercial production of vehicles at the Honsha plant in 1938. From September 1947, it sold its small-sized vehicles under the name â€Å"Toyopet†. The company focused on truck production during World War 2 for the Japanese army. Japan was hit by serious financial difficulties after World War 2. For this reason, TMC faced a financial crisis in 1949 that brought it to the brink of bankruptcy (Toyota Motor Corporation 1). During the financial crisis that the company faced, it only produced 300 trucks in 1950, and almost went out of business. To deal with the financial crisis, a consortium of banks lent TMC a loan to revamp itself. On obtaining the loan, the company began eliminating excess workers through layoffs and reduction of wages. In 1950, the company started the Toyota Motor Sales Company that lasted only until 1982 because it was merged with the TMC. Toyota launched the Crown Deluxe, Toyopet Master, and Toyopet Crown in 1955 (Toyota Motor Corporation 1). In 1950, Kiichiro Toyoda resigned as the president of TMC. Taizo Ishida took over the company’s presidency and was credited for focusing his efforts on investing in equipment. One such example was  when he led the establishment of the Motomachi plant.

Reflection paper Essay Example | Topics and Well Written Essays - 250 words - 14

Reflection paper - Essay Example Every now and then we got to read students’ essays on the same topic or type of essay we were willing to write and that has greatly helped me since I got to understand what was right or wrong with it, in addition to not only evaluating the essay but also getting the chance to share my feedback with the rest of the class. Reading other people’s essays and listening to the professor talking about them makes me know what to include in my essays as well as how to make them efficient. The most effective thing I have done is working on the run on sentences because they helped me a lot and made me aware of what to avoid while writing my essays. The peer review has also helped me a little bit because apart from seeing my group’s papers and finding things to develop my essay more, I also get feedback from my group that assists me fix and make my essay even better. I attended the first conference which was very helpful since it helped me avoid getting a terrible score. On showing my essay to the professor, he advised me to change all of it because it wasn’t the kind he had requested for. He further gave me a chance to re-write my essay, as per his instructions so as to get a good grade. I feel that the professor teaching us English is doing his best in teaching us what we need to learn; which is a very commendable job

Reflection on Learning Skills Development

Reflection on Learning Skills Development Learning Preferences Learning is a life long process and can be had in various shapes and forms. It can be based on education, experience, formal training etc. Every individual has his preferred way of learning which can change during the course of his lifetime. Eg. Individuals can prefer class-room learning when they are young and formal training when they grow old. Usually learning based on experience is considered one of the best ways to learn, but George Bernard Shaw (cited in Moyer, 2007) believes that experience doesn’t guarantee learning. He points out that men are wise in proportion, not to their experience, but to their capacity for experience and one needs to pay attention to find the lessons. Formal training is another way to learn and has been greatly successful within organizations over the years. But, Peter Drucker in his article â€Å"Managing Oneself† (HBR March–April 1999; pg 148) doubts the effectives of formal training by stating that training can be an impediment to learning because it is based on the assumption that there is only one right way to learn. Education and class-room based learning have traditionally been a preferred mode of learning. Rapid rise in technology and its applications has meant ready and continuous access to training and business communications which has meant that learning can now be more timely, specific and synchronous (Sullivan, 2003). Today’s generation want to be connected to instant messaging and short, highly-focused training that can be quickly downloaded and accessed via mobile phones, PDAs, or MP3 players(Ware, 2007; pg 58). Every learning technique has its advantages and limitations and the most preferred learning technique depends on variables like age, life-style, receptiveness and responsiveness of the brain, patience etc. Preferred Team Roles Teams have become a key component in organizations; properly working teams are now central to the organizations health. (Fisher at el., 1998) Because of the growing emphasis on team-working, a lot of research has gone into the structure, dynamics and the operations of the team. This has led to segregating team member by their functionality and the roles and responsibilities they entail as a part of the team. Belbin (1981) identified eight different roles within the team with each member complementing the others strengths and compensating for the weaknesses. Belbin classified and named his team roles as: The plant – Is a problem solver and has innovative, creative and unorthodox way of dealing with situations. Has a strong ownership of ideas. The resource investigator – Is the networking member the team that explores opportunities through new and pre-existing contacts. Is an extrovert, enthusiastic individual having good communication skills. The coordinator – Coordinates different activities of the team and acts as a chairperson. Is responsible for most of the decision making and is normally more experienced than other members. The Shaper – Overcomes obstacles with his drive and courage. Thrives on pressure. Monitor-Evaluator – Has good judgment and the ability to look at the bigger picture. Has more strategic focus. TeamWorker – Responsible for avoiding conflicts and making sure the team gels together and coordinates well. Implementer – Responsible for turning ideas into actions. Completer – Is a perfectionist responsible for finishing the project on time. (Belbin, 1993) Attitudes to Decisions making No matter what sector or industry people work in, they have to make decisions. Decision making involves risk because, most often than not, the outcome cannot be guaranteed. By definition, a decision involves choice and therein lie the difficulty- making the right choice. (McGuire, 2002) The degree of risk involved is greater if the decision is made at the strategic level as compared to the tactical and operational level. Normal attitudes to decision making include: Indecisiveness – People try to evade decision making because it involves risk. Faced with choices and being unclear about which one to make leads to indecisiveness and inaction. Over Analysis – Another attitude to decision making can be over-analyzing options to make sure the correct decision is made. Langdon (2001) calls it ‘paralysis by analysis’ syndrome which means inaction caused by too much thinking. Decisions made on past experiences (historical evidence)– Decisions, at times, are also made by on past experiences without considering the current situation. Eg. If faced with a similar problem as in the past, there is likelihood that the decision similar to the one made in the past will be made. Other attitudes to decision making include decisions made in haste and decisions made without proper consultation with others. Leadership and management skills Leadership is the ability to obtain results from others through personal direction and influence and requires management of self and management of others. Leadership and management differ in the way that management is concerned with ensuring things remain as they are and is often done by standard practice and regulation; leadership involves possessing vision, and the ability to communicate that vision. Leaders should possess the following skills Problem Solving – Problem solving involves identification and definition of the problem, generation of a number of solutions that could be accepted, evaluation of alternatives and their outcomes. An important attribute within problem solving is, communication, in particular, listening skills, as various opinions and possible solutions are being generated. The leader has to see the big picture and choose the best possible solution (decision-making). Decision making – Decision making goes hand in hand with problem solving (as cited in the last paragraph). Every aspect of leadership requires decision making. Delegation, for example, requires the manager to decide which individual is suited for specific tasks and how to distribute work in an optimal and best possible way. Communication – It is very important that the leader has regular and open communication with both the customer and the team members. Change-management – Managing change is also vital to effective leadership because changes might be requested by the stakeholders, caused by unexpected events. Therefore, it is important that the leader has the skills to manage and control change and make sure that the impact of change on accomplishing objectives is kept to a minimum. Management skills Independent of the leadership ability, managers has been studied to have different styles. The style chosen by a manager depends on the assumptions that they make about subordinates, what they think they want and what they consider their attitude towards work to be. Managers have to provide direction to the team, the drive and motivation to work as a part of the team, represent the purpose of team working and working as a group. All the components mentioned below are essential traits of a leader. There has been a widespread acceptance that leadership is an essential management component but it has proved to be difficult to identify the elements of effective leadership and how effective leadership relates to good management practices. (James Walke, 2004) It is worth pointing out that there is no one best style of leadership that is equally effective for all circumstances. The best leadership style is the one that fulfills the need of the group the most, while at the same time satisfy the needs of the external stakeholders. Personal Development plan Areas of development Author’s weaknesses lie in the following areas: Delegation skills – The author is not very good at delegating tasks and has an inherent weakness to doubt others capabilities. He is more comfortable when most of the crucial responsibilities and decision making rests in his own hands and where he just tells the team what to do. Communication – Communication in one of the author’s other weaknesses. This takes off from his delegation style, because he believes in centralized decision making and the need to communicate with subordinates or other team members is seldom realized. Negotiation – The author also finds himself lacking in negotiation skills at times. He is good at understanding and knowing the background to the problem but it’s the bargaining phase of negotiation that the author is not very good at (especially in project management environment). Strengths (Key Skills) Author’s strengths lie in: Organization and Planning – The author excels at organization and planning and makes good use of planning tools. He takes time out to decide on the critical activities and the slack and apportion responsibilities accordingly. He has a clear understanding of the tasks ahead and prioritizes tasks according to their order of importance. Motivation – The author is a highly motivated individual who could turn on creative juices, fight against odds and walk the extra mile to reach set goal and attain objectives. Change Management – Embracing change is another one of the author’s positive traits. He has always identified the need to change and how change can be effectively implemented with least resistance. Background Preferred team role The author’s preferred team role based on his capabilities is that of the ‘plant’ (going by Belbin’s classifications). Armed with strong theoretical basics and practical training, he has a strong ownership of ideas. The author also possesses an unorthodox way (out of the box thinking) of dealing things and is always looking for new and better ways to tackle issues and solve problems. He is skeptical to an all-logical approach to problem solving and does not always adhere to norms and proven ways of doing things. Author’s weakness lies in his ability to work under pressure and to consequently avoid situations that may entail pressure. Decision making style The author does make decisions after a proper analysis of the situation and how the decision affects individuals and the organization. His decision making style involves a process of elimination where a final decision is taken after eliminating alternatives. The author’s weaknesses lie in giving minimal consideration to external factors. What is required for decision making is the use of appropriate decision making tools. SWOT (Strengths, Weaknesses, Opportunities and Threats) is one such tool which helps to assess the internal and external decision making environment. Edward de Bono’s ‘six thinking hats’ is another tool for making team decisions. Before making a decision, the author has to make sure that the impact on external stakeholders is also considered. One of the other weaknesses of the author is the tendency to rush with decisions (haste). To overcome this, the author has to make sure that the issue is defined properly, all the information and alte rnatives are carefully considered and all the options weighed and evaluated before the decision is made. Preferred learning style The author’s preferred mode of learning is through hands-on training after having a firm theoretical knowledge of the basic concepts. A good way to learn for the author would be to start with a theoretical learning exercise through a tutor based class-room course and then having to execute the learning with hands-on training under some supervision. This would be an ideal scenario as it blends theory and practice. It might take some extra time to carry out the training, but at the end of it, the author would have added sufficient skills and is likely to be more efficient while working. This will also make sure sufficient time is allocated to train individuals; training is not rushed with and does not cover just one aspect (theoretical or practical). Goals The author sets goals based on his strengths. He makes sure that the goal is specific. A specific goal like improving profitability by 3% in the next financial year gives direction to the efforts. Also the author makes sure that the set goals can be measured (in relative or absolute terms) and are attainable. If goals are far too optimistic (unrealistic) and beyond reach, then it tend to have an adverse effect on motivation. The author only sets goals which he believes can be accomplished. It is made sure that the goal is attained within a specific time frame. Goal setting is a variable process for the author where the goal can be varied depending on external and unforeseen circumstances. Goals are set based on authors past performances and it is made sure that the goals are neither too easy nor too difficult to attain. Planning A plan is devised by the author to attain goals. Firstly, the author lists key skills required to attain the goal along with other requirements and constraints. Then a structure is given to the planning process to bring all aspects of planning together into a coherent, unified process. The planning structure includes analysis of opportunities, identification of aims, exploring of options, selection of the best option, evaluation of the plan followed by implementation and closure of the plan. Opportunities Setting up a goals and giving direction to the career to achieve that goals opens up several opportunities. The first opportunity is to realize the shortcomings and working on improving them. When we list our goals, we build our self-image and we see ourselves worthy of these goals which acts as a motivating agent. (Hosking Bass, 2001) As a result, we try our best to develop the traits and personality that allows us to possess those goals. Improving on weaknesses and learning through experience are the two best opportunities to be gained from the self development process. Progress The author makes use of indicators like Gantt Charts (See Appendix 1) and Network diagrams (See Appendix 2) to track progress. Gantt charts help in setting a time frame that allows carrying out all the necessary steps. The author makes sure that the critical activities are paid sufficient attention and sufficient time is allocated as ‘slack’. Authors skill set also includes soft skills such as impulse to lead and attain objectives, anticipatory skills to adjust the goals according to the changing environment and empowerment skills. Successful plans make optimal use of skills, experience and specialist knowledge. References Belbin, R.M (1981) Management Teams –Why they succeed or fail, London, Butterworth-Heinemann Belbin, R.M (1993) Team roles at Work, Oxford, Butterworth-Heinemann Drucker, P (1999) People and Performance: Managing Oneself ,Harvard Business School Press Books, p1, pg 148 Fisher et al., (1998) The distribution of Belbin team roles among UK managers, Personnel review, volume 29, 2, pg 1-14 Janice, W (2007) TRAINING Tomorrows WORKFORCE., Rosemary; Kerschenbaum, Steve. T+D, Vol. 61 Issue 4, p58-60, Hall, B (2007) Five Ways to Use Social Networking for Learning.,. Chief Learning Officer, Vol. 6 Issue 5, p17-17 Hosking, D. M., Bass, A. (2001). Constructing changes in relational processes:Introducing a social constructionist approach to change work. Career Development International, 6/7, 348-360. McGuire, R (2002) Decision Making, The Pharmaceutical Journal, Vol 269, pg 647-649 Moyer, D. (2007) The Stages of Learning,. Harvard Business Review, Vol. 85 Issue 5, p148-148 Mumford, A (2002) Horses for Courses, Learning Centre, Accessed from http://peoplemanagement.co.uk Date accessed 21/05/2007 Sullivan, A. K., Strang, H. R. (2002-2003). Bibliotherapy in the classroom: Using literature to promote the development of emotional intelligence. Childhood Education,79, 74-80.

Princess Diana Spencer Essay -- biographies bio biography

Princess Diana Spencer As I relax on a Sunday evening, breathe in fresh air before I enter my chamber, I catch a glimpse of something magically beautiful. With a long silk blue dress and a pearl-diamond tiara on her golden hair, the Lady, the Princess, the beauty of the world walks down the steps to the cheering crowds. She gives hope to her people when there is none. Sitting here, I feel her warm smile full of love and joy. This is my Diana, the light of this world! Diana’s childhood was full of wealth but lacked the happiness of a bonded family. Diana was born on a warm first day of July 1961. Diana lived in a very large house that had many facilities where she spent time with her siblings and Prince Andrew and Edward. Diana and her siblings were raised to be on their best behavior, and had self-discipline, respect, and proper etiquette taught by her noble parents. However, her parents started fighting when she was just six years old. The following year her parents divorced. Diana and her siblings were to stay with their father. Even though, nannies and servants took care of Diana and her little brother and sisters, the motherly care was missing. Diana felt abandoned and her soul felt deeply wounded. This was especially true for young Charles who missed his mother in an indescribable way. This was the time when Diana discovered her talent. By opening her heart to others, she numbed her own pain. Diana became a substitute mother for Charl es. She protected him and gave him love and warmth. Then, a scene of horror occurred for the nine-year-old Diana Spencer. Her father decided to send her to a boarding school. Diana was so shy, so vulnerable that it took her a long time before she could finally feel at ease in her new enviro... ...n the evening of Sunday the 31 of August. The coffin was moved several times until it was finally left at St. James’s Palace until the funeral on Saturday, September 6, 1997, in Westminster Abbey. After the funeral, the coffin was taken to the family estate at Althorp, for a private interment. The Princess was buried on an island in the center of an ornamental lake. Once I said that Diana is the light of this world. Now I know that these words were not strong enough. What she gave this world, to us her people is indescribable, but we do not seem to understand this until it is gone. Diana was a remarkable woman who gave light, hope, and love to this world. However, at the moment where she finally gained happiness and freedom she was killed. The harsh world took Diana away and left only the memories of this light, a gift from God, our Princes Diana in our hearts.

Epiphany

Who I Am As a child I grew up telling myself and everyone else that I never wanted to get married and have children. I watched my mother get married and divorced twice and seen what kind of pain that inflicted on her and us kids. I thought that I would be a better person if I stayed single and didn't have any kids to worry about. Of course I fell in love early in adulthood and decided to have children. A few years later my fear f becoming like my mother in the aspect of marriage, divorce and having kids came alive.I felt like such a fool for allowing that to happen to me. Usually by the time I get home from work and picking up the kids, It Is late and I do not feel like taking the time to actually cook a meal. One evening we got home earlier than we usually do so I decided to fix dinner, sit down and actually eat as a family. I can remember myself standing In front of the stove thinking of the frustrating long day of work I had, getting aggravated because the kids were running around the souse.The kids were playing and being loud which Is what a 4 year old boy and 4 year old girl would do. Then It suddenly becomes quiet and Patrick comes to me and says â€Å"Mommy, you know what? † I say with an annoyed tone of voice â€Å"What Patrick? † He says â€Å"your superman. † I picked him up and gave him a big hug. In that moment I realized that out of all that has happened to me In my life, I am truly grateful that I have my children and that I am actually a better person because God brought them Into my life.

Alcohol Research Paper Essay

Alcohol plays too significant a role in society today and should be an after thought as opposed to the most essential addition to any social event. Alcohol creates numerous social, economic, and health problems that could very easily be stopped if it played a less influential role in every day events. The use of alcohol is prominent in, but not limited to three social circles that include students, family groups, and religious gatherings. Experts have much to say about alcohol use and abuse in these three categories, including all of the negative aspects of drinking. Social drinking is a common occurrence around America. Whether it is after work or after a football game, white collar or blue, two-thirds of the American population sit down at least once a week to enjoy an alcoholic beverage (Med. unc. edu). Many of these people do not realize that drinking is what leads to uncontrolled behavior, drunk driving, and in the long run, addiction. They are thinking only of the short-term effects, not the negative long-term consequences. People who regularly turn to alcohol eventually begin to neglect their families and other responsibilities, consequently wrecking the lives of loved ones and their own as well. While the lasting negative effects of alcohol use are spewed daily through the media, the problems will not stop until society completely understands how alcohol can indeed pose a serious threat to the nations social welfare. Alcohol has an adverse effect on the economy. The consequences of alcohol abuse and dependence cost the nation an estimated $99 billion each year (Gordis, 209). It is tax money that pays for alcoholics who both live on the street and are barely getting by or who are in government-funded hospitals and institutions. The United States should either find an alternative way to take care of these people or perhaps raise liquor taxes. Either one of these options would conceivably minimize the economical problems caused by alcoholic beverages. It is not the responsibility of the people as a whole to take care of the homeless people who have fallen prey to the lure of alcohol related problems. As of 1991, about 14 million Americans met medical diagnostic criteria for alcohol abuse or alcoholism. There are numerous health problems that are linked to drinking. For instance, if alcohol is consumed during pregnancy, birth defects may result, worse, the baby could be born addicted to alcohol (Kellam, 30). High doses of alcohol have also been found to delay puberty in females and slow bone growth and result in weaker bones (Windle, 179). One of the main risks of drinking alcoholic beverages is having a stroke. A review of epidemiological evidence concludes that moderate alcohol consumption increases the potential risk of strokes caused by bleeding (Camargo, 1620). Another medical problem that involves alcohol is the use of prescription medications. Alcohol may interact harmfully with more that 100 medications, including some sold over the counter. The effects of alcohol are especially augmented by medications that depress the function of the central nervous system, such as sleeping pills, sedatives, and antidepressants, and certain painkillers (Thomas, 336). Upon understanding the risks of drinking, some people would surely stop. Better health is a good reason to do so. One of the main groups of alcohol users is high school and college students. Despite a legal drinking age of 21, many young people in the United States consume alcohol. There are several factors that put youth at risk for drinking and for alcohol-related problems and also several consequences of their drinking. Thirteen- to fourteen- year-olds are at high risk to begin drinking. This is a confusing stage in their life and they are easily pressured into doing things they would not normally do. Also at high risk are twins and adopted children. Studies of these two groups demonstrate that genetic factors influence an individual’s vulnerability to alcoholism. Children of alcoholics are more likely than children of nonalcoholics to imitate drinking during adolescence and develop alcoholism, but the relative influence of environment and genetics have not been determined and vary among people (Chassin, 453). Advertising has also been found to play an influencing role in adolescents’ decision to drink. Research has assessed the effects of alcohol advertising awareness on intentions to drink. In a study of fifth- and sixth-graders’ awareness measured by the ability to identify products in commercials with the product name blocked out awareness had a small but statistically significant relationship to positive expectancies about alcohol and intention to drink as adults (Grube, 257). Although there are many risk factors inviting youths to drink, one of the most prevalent is peer drinking and acceptance of drinking. If one minor sees another drinking he would most likely find it acceptable and join his friend. If all of these risk factors were reduced, say, less advertising of alcohol where children will likely be influenced, children would not find it as acceptable to drink and would probably not start off so young or abstain wholly. Though the prevalence of binge drinking varies among campuses, the overall statistics are alarming. A 1993 survey by 18,000 students at 140 colleges in 40 states found that 44% of the students drank heavily (med.unc. edu). In an effort to curb students thirst for alcoholic beverages, many schools are trying to come up with alternatives to promoting social events that involve alcohol. Colby University has come up with a new program that offers students an alternative to getting ? sloshed. ‘ Faculty and students there have formed a committee that will recommend a reorganization of social functions. One of their recommendations was that the student association spend at least 50% of their funds exclusively alcohol free events. The other 50% of the funds may be used for entertainment, decorations, or refreshments, but may not be used for the purchase of alcohol (colby. edu). More schools should take part in this kind of rehabilitation, not only does it give the school a positive reputation, but it gives the student s more time to concentrate on the reason that they are there which is to learn. Serving food, non-alcoholic drinks, offering activities and entertainment such as games and music, and ceasing to give alcohol two hours before the end of the party are all ideas that will promote safe social scenes and responsible parties. One way to deter younger drinkers from becoming addicts is to step up the punishment for law-breakers who have a blood alcohol concentration indicating public intoxication. Whether it is as minor as carrying a fake identification card or as major as a drunk driving accident, offenders who break the law while legally intoxicated should be punished to the full extent of the law. Alcohol abusers, these risk takers and law-breakers, may realize after being punished once or twice that this is not the path they should take. Sobriety is a great thing, and the choice to be sober is one that should have positive connotations as opposed to the negative ones that go with drinking and being drunk. Learning at a young age that alcohol is not the great thing that everyone makes it out to be is a step in the right direction. We really should start now on a program that gives every child from kindergarten to college factual, unbiased training about alcohol. Then in a couple of generations we’d see fewer problems. Most people would have learned to drink responsibly. (Weiner, 93) The earlier people learn, the best it will be for them and society in general.

Geography of the Ganges River

Geography of the Ganges River The Ganges River, also called Ganga, is a river located in northern India that flows toward the border with Bangladesh (map). It is the longest river in India and flows for around 1,569 miles (2,525 km) from the Himalayan Mountains to the Bay of Bengal. The river has the second greatest water discharge in the world, and its basin is the most heavily populated in the world with over 400 million people living in the basin. The Ganges River is extremely important to the people of India as most of the people living on its banks use it for daily needs such as bathing and fishing. It is also significant to Hindus as they consider it their most sacred river. The Course of the Ganges River The headwaters of the Ganges River begin high in the Himalayan Mountains where the Bhagirathi River flows out of the Gangotri Glacier in Indias Uttarakhand state. The glacier sits at an elevation of 12,769 feet (3,892 m). The Ganges River proper begins farther downstream where the Bhagirathi and Alaknanda rivers join. As the Ganges flows out of the Himalayas, it creates a narrow, rugged canyon. The Ganges River emerges from the Himalayas at the town of Rishikesh where it begins to flow onto the Indo-Gangetic Plain. This area, also called the North Indian River Plain, is a very large, relatively flat, fertile plain that makes up most of the northern and eastern parts of India as well as parts of Pakistan, Nepal, and Bangladesh. In addition to entering the Indo-Gangetic Plain in this area, part of the Ganges River is also diverted toward the Ganges Canal for irrigation in the Uttar Pradesh state. As the Ganges River then flows farther downstream, it changes its direction several times and is joined by many other tributary rivers such as the Ramganga, Tamsa, and Gandaki rivers to name a few. There are also several cities and towns that the Ganges River passes through on its way downstream. Some of these include Chunar, Kolkata, Mirzapur, and Varanasi. Many Hindus visit the Ganges River in Varanasi as that city is considered the holiest of cities. As such, the citys culture is also closely tied into the river as it is the most sacred river in Hinduism. Once the Ganges River flows out of India and into Bangladesh, its main branch is known as the Padma River. The Padma River is joined downstream by large rivers like the Jamuna and Meghna rivers. After joining the Meghna, it takes on that name before flowing into the Bay of Bengal. Before entering the Bay of Bengal however, the river creates the worlds largest delta, Ganges Delta. This region is a highly fertile sediment-laden area that covers 23,000 square miles (59,000 sq km). It should be noted that the course of the Ganges River described in the above paragraphs is a general description of the rivers route from its source where the Bhagirathi and Alaknanda rivers join to its outlet at the Bay of Bengal. The Ganges has very complicated hydrology, and there are several different descriptions of its overall length and the size of its drainage basin based on what tributary rivers are included. The most widely accepted length of the Ganges River is 1,569 miles (2,525 km), and its drainage basin is estimated to be about 416,990 square miles (1,080,000 sq km). The Population of the Ganges River The Ganges River basin has been inhabited by humans since ancient times. The first people in the region were of the Harappan civilization. They moved into the Ganges River basin from the Indus River basin around the 2nd millennium B.C.E. Later the Gangetic Plain became the center of the Maurya Empire and then the Mughal Empire. The first European to discuss the Ganges River was Megasthenes in his work Indica. In modern times the Ganges River has become a source of life for the nearly 400 million people living in its basin. They rely on the river for their daily needs such as drinking water supplies and food and for irrigation and manufacturing. Today the Ganges River basin is the most populated river basin in the world. It has a population density of about 1,000 people per square mile (390 per sq km). The Significance of the Ganges River Aside from providing drinking water and irrigating fields, the Ganges River is extremely important to Indias Hindu population for religious reasons as well. The Ganges River is considered their most sacred river, and it is worshiped as the goddess Ganga Ma or Mother Ganges.   According to the Myth of the Ganges, the goddess Ganga descended from heaven to dwell in the waters of the Ganges River to protect, purify and bring to heaven those who touch it. Devout Hindus visit the river daily to offer flowers and food to Ganga. They also drink the water and bathe in the river to cleanse and purify their sins. Also, Hindus believe that upon death the waters of the Ganges River are needed to reach the World of the Ancestors, Pitriloka. As a result, Hindus bring their dead to the river for cremation along its banks and afterward their ashes are spread in the river. In some cases, corpses are also thrown into the river. The city of Varanasi is the holiest of cities along the Ganges River and many Hindus travel there place ashes of their dead in the river. Along with daily baths in the Ganges River and offerings to the goddess Ganga there are large religious festivals that occur in the river throughout the year where millions of people travel to the river to bathe so that they can be purified of their sins. Pollution of the Ganges River Despite the religious significance and daily importance of the Ganges River for the people of India, it is one of the most polluted rivers in the world. Pollution of the Ganges is caused by both human and industrial waste due to Indias rapid growth as well as religious events. India currently has a population of over one billion people, and 400 million of them live in the Ganges River basin. As a result, much of their waste, including raw sewage is dumped into the river. Also, many people bathe and use the river to clean their laundry. Fecal coliform bacteria levels near Varanasi are at least 3,000 times higher than the what is established by the World Health Organization as safe (Hammer, 2007). Industrial practices in India also have little regulation and as the population grows these industries do as well. There are many tanneries, chemical plants, textile mills, distilleries and slaughterhouses along the river and many of them dump their untreated and often toxic waste into the river. The water of the Ganges has been tested to contain high levels of things like chromium sulfate, arsenic, cadmium, mercury and sulfuric acid (Hammer, 2007). In addition to human and industrial waste, some religious activities also increase the pollution of the Ganges. For example, Hindus believe that they must take offerings of food and other items to Ganga and as a result, these items are thrown into the river on a regular basis and more so during religious events. Human remains are also often placed into the river. In the late 1980s Indias prime minister, Rajiv Gandhi began the Ganga Action Plan (GAP) to clean up the Ganges River. The plan shut down many highly polluting industrial plants along the river, and allotted funding for the construction of wastewater treatment facilities but its efforts have fallen short as the plants are not large enough to handle the waste coming from such a large population (Hammer, 2007). Many of the polluting industrial plants are also continuing to dump their hazardous waste into the river. Despite this pollution, however, the Ganges River remains important to the Indian people as well as different species of plants and animals such as the Ganges River dolphin, a very rare species of freshwater dolphin that is native only to that area. To learn more about the Ganges River, read A Prayer for the Ganges from Smithsonian.com.

Should gay marriage be legal Essay Example | Topics and Well Written Essays - 2250 words

Should gay marriage be legal - Essay Example I think not. Legalizing gay marriage is not simply about protecting the rights of homosexuals. It’s not about treating fairly the so addressed minority of the population, the mythic 3 percent figure of Americans (Cameron 12). Gay marriages will arouse deep structural changes by transforming beliefs, questioning values, and institutionally proclaiming something that has long been rejected by human nature as valid, accepted and official. In this essay I am not trying to be a moralist, saying what people should or should not believe in. I simply want to question a change that is so unnatural and intrusive to me, that the argument saying â€Å"it’s their inherent human right† is not strong enough to accept it. Today the world is changing so fast and many core values are simply swept away by fashion, carelessness and eccentricity. The civil rights activists once playing the important part for this society to overcome racial or female intolerance have now shifted their efforts into new directions, pleading for further liberation of sexist rights. Now, that the so widely proclaimed same-sex marriages are in the limelight, it pays to stop and think, will their legalization really create added value to society or, on the contrary, will it actually cause harm by undermining the institution of marriage. Marriage represents a legal bondage, an institution that is recognized by church, and society. This is the couple’s official declaration for long-term commitment to one another. Marriage is a unique contract, different from simply sharing property or setting up a new business; it establishes a relationship that does not exist for people who are simply living together (Cline). When people get married, they become a social unit with strong kinship ties regarded by society as one unity. When gay couples want to contract a marriage, they actually ask for society’s

The electric car , Practicalities and Prospects Essay

The electric car , Practicalities and Prospects - Essay Example In the context of this reality some of the states in the U.S. have passed laws requiring that a minimum percentage of sales made must be zero emission vehicles. Although the law does not explicitly mention electric car, they are the most feasible alternative as of now (Lave, 2005). Also, helping the case for electric cars are chemicals such as carbon monoxide, nitrogen oxides and volatile organic compounds are extremely hazardous to humans as well as the ecosystems they live in. Several studies have shown that the exhaust gases released by petroleum run cars are the contributor to this pollution. This pollution has no small part to play in the general increase in temperatures across the world, also called â€Å"global warming†. At this juncture the introduction of electric cars in the market is not only a good business opportunity but a better alternative for humans and their environments alike. In this respect, the prospects are quite good for electric cars in the near future, until a better technology replaces it (Newbery, 2001). On the flip side generating electricity for recharging batteries can lead to significant harm to the environment. A transition to electric cars, as made compulsory already in some parts of the world, is proven to be no more environment friendly than cars that run on low-emission petrol. Factories making lead-acid batteries would release higher levels of toxic lead. Low-toxicity batteries on the other hand are not yet suited for mass manufacture (Ochoa, 1997). The possible dangers of rechargeable batteries are illustrated in the following passage: â€Å"For vehicles that are to be mass produced in the future, lead-acid batteries are likely to be the only practical technology. Smelting and recycling the lead for these batteries will result in substantial releases of lead to the environment. Lead is a neurotoxin,